Ibnosina Journal of Medicine and Biomedical Sciences

CASE REPORT
Year
: 2021  |  Volume : 13  |  Issue : 4  |  Page : 231--235

Severe hyperglycemia in an insulin-deficient patient with type 2 diabetes responding well to oral antidiabetic therapy


Akrem Y M. Elmalti, Mamoun Mukhtar, Sijomol Skaria, Wafa Harbagi 
 Rashid Centre for Diabetes and Research, Ajman, UAE

Correspondence Address:
Dr. Akrem Y M. Elmalti
Rashid Centre for Diabetes and Research, Ajman
UAE

Type 2 diabetes mellitus (T2DM) is a chronic, progressive disease characterized by a steady decline in beta-cell function and insulin resistance. As a result, most patients with T2DM may require treatment with insulin after 15–20 years of diagnosis. Various pathophysiological defects were identified leading to hyperglycemia, including reduced insulin secretion due to beta-cell failure. They reduced beta-cell mass and a defect in insulin secretion, which leads to a relative insulin deficiency in these patients requiring insulin treatment. Most international guidelines recommend starting insulin treatment in patients with poor glucose control, mainly if the glycated hemoglobin (HbA1c) is above 9% with the presence of symptoms, especially in relatively newly diagnosed patients with T2DM. We present a 45-year-old patient with T2DM of 5 years duration who attended our center with severe hyperglycemia with evidence of insulin deficiency both clinically and biochemically, who responded well to oral antidiabetic agents achieving adequate glycemic control.


How to cite this article:
M. Elmalti AY, Mukhtar M, Skaria S, Harbagi W. Severe hyperglycemia in an insulin-deficient patient with type 2 diabetes responding well to oral antidiabetic therapy.Ibnosina J Med Biomed Sci 2021;13:231-235


How to cite this URL:
M. Elmalti AY, Mukhtar M, Skaria S, Harbagi W. Severe hyperglycemia in an insulin-deficient patient with type 2 diabetes responding well to oral antidiabetic therapy. Ibnosina J Med Biomed Sci [serial online] 2021 [cited 2022 May 18 ];13:231-235
Available from: http://www.ijmbs.org/article.asp?issn=1947-489X;year=2021;volume=13;issue=4;spage=231;epage=235;aulast=M.;type=0