|LETTER TO EDITOR
|Year : 2020 | Volume
| Issue : 2 | Page : 141
Maternal and fetal outcomes in patients with systemic lupus erythematosus
Mahmood Dhahir Al-Mendalawi
Department of Pediatrics and Child Health, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
|Date of Submission||01-Jun-2020|
|Date of Decision||02-Jun-2020|
|Date of Acceptance||02-Jun-2020|
|Date of Web Publication||27-Jun-2020|
Prof. Mahmood Dhahir Al-Mendalawi
P. O. Box: 55302, Baghdad Post Office, Baghdad
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Al-Mendalawi MD. Maternal and fetal outcomes in patients with systemic lupus erythematosus. Ibnosina J Med Biomed Sci 2020;12:141
|How to cite this URL:|
Al-Mendalawi MD. Maternal and fetal outcomes in patients with systemic lupus erythematosus. Ibnosina J Med Biomed Sci [serial online] 2020 [cited 2022 Jul 2];12:141. Available from: http://www.ijmbs.org/text.asp?2020/12/2/141/288205
In January-March 2020 issue of the Ibnosina Journal of Medicine and Biomedical Sciences, Ahmed et al. reported that preexisting hypertension and secondary antiphospholipid syndrome were correlated with an increased risk of pregnancy complications in Libyan pregnant women with systemic lupus erythematosus (SLE).
There are a few notable methodological limitations that ought to be considered. In the study methodology, Ahmed et al. established that the diagnosis of SLE was based on fulfilling at least four of the 1997 American College of Rheumatology (ACR) criteria. It is worth mentioning that the 1997 ACR criteria have numerous limitations, namely equal weighting of features that differ in the clinical relevance, bias toward longer duration and more severe disease, and exclusion of SLE patients from research that do not fulfill the four criteria. Hence, a good number of pregnant women with SLE who did not meet the four criteria of the 1997 ACR criteria were expected to be misdiagnosed and could not be enrolled in the study. This might consequently seriously influence the study results.
A newer classification criteria for SLE supported jointly by the European League Against Rheumatism and ACR have been proposed utilizing strict methodology with a multidisciplinary input. The newer classification criteria have both higher sensitivity (96.1%) and specificity (93.4%) in comparison with 82.8% sensitivity and 93.4% specificity of the 1997 ACR criteria. Consequently, employing the newer diagnostic SLE criteria could have been better in elucidating the adverse outcomes and their likely predictors in SLE pregnant women.
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Conflicts of interest
There are no conflicts of interest.
| References|| |
Ahmed AM, Ibkhatra SA, Elbraky FM, Alsaeiti KD. Maternal and fetal outcomes in patients with systemic lupus erythematosus. Ibnosina J Med Biomed Sci 2020;12:33-7. [Full text]
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. 2019 European League Against Rheumatism/American College of rheumatology classification criteria for systemic lupus erythematosus. Arthritis Rheumatol 2019;71:1400-12.