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Year : 2016  |  Volume : 8  |  Issue : 2  |  Page : 28-51

Histopathologic identification and pattern recognition of common viral infections in the general pathology practice: An illustrated review

1 Saint Louis University School of Medicine, ST. Louis, MO 63104, USA
2 Department of Medicine, Indiana University, Indianapolis, IN, 46202, USA
3 Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus OH 43205, USA

Correspondence Address:
Samir B Kahwash
Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus OH 43205
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1947-489X.210214

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Pattern recognition and cytologic features remain essential diagnostic tools in pathology. Viral cytopathic effect may be the first clue to a diagnosis of a viral infection. This paper aims to provide a brief illustrated summary of the histopathologic changes caused by commonly encountered and rare viruses. The list of viruses discussed with characteristic viral inclusions or distinctive cytopathic effect includes cytomegalovirus, adenovirus, herpes virus (herpes simplex virus and varicella zoster virus), human papillomavirus, respiratory syncytial virus, parvovirus, poxvirus (molluscum contagiosum virus), and polyoma virus (JC virus and BK virus). Also reviewed are the characteristic histologic and cytopathic changes for Epstein-Barr virus (EBV), Paramyxoviruses (human parainfluenza virus and measles virus), human immunodeficiency virus (HIV), and hepatitis B virus.

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